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Seminar "The Progress in Understanding Alzheimer's Disease"

The 10th scientific seminar ‘Modern demography’ was held on the 17th of April.Anatoliy I. Yashin, PhD, ScD, research professor and co-Director of Biodemography of Aging Research Unit (BARU), SSRI, Duke University, USA presented a paper " The Progress in Understanding Alzheimer's Disease".

In his speech, Anatoliy I. Yashin outlined the situation with Alzheimer's Disease (AD) and other forms of dementia in the world, presented the public with the characterizations of AD and dwelled on two types of this disease and their pathological hallmarks. A.I. Yashin also mentioned the directions and some results of the research department's work on the problems of biodemography of ageing at Duke University, USA. The author also considered the reasons which predetermine the significance of conducting research in this field, and also went into the details of modern hypotheses explaining the causes of Alzheimer's disease, in particular mentioning such pathological signs of the disease as beta amyloids, tau proteins, etc.

Four main research areas on Alzheimer's disease and the newest revealed pathological signs of this disease were considered during the presentation. The speaker also considered the causes that predetermined the lack of effective drugs against Alzheimer's despite 20 years of research in this field.

A.I. Yashin also examined in detail the role of individual ageing processes and the role of cellular stress in the onset and development of Alzheimer's disease. The most important results obtained via genetic and genomic studies of Alzheimer's disease  (in particular, during the studies devoted to the determination of the group of genes involved in the response to cellular stress and their functional properties) were also presented during the speech. In conclusion, the current situation with the funding of Alzheimer's disease research in the United States was reviewed.
Presentation by A.I. Yashin